Publications

An overview of papers, editorials reviews and publihed abstracts:

  • Gilles Defraene, Matthew La Fontaine, Simon van Kranen, Bart Reymen, José Belderbos, Jan-Jakob Sonke, Dirk De Ruysscher. Radiation-Induced Lung Density Changes on CT Scan for NSCLC: No Impact of Dose-Escalation Level or Volume. International Journal of Radiation Oncology Biology Physics, Volume 102, Issue 3, 1 November 2018, Pages 642-650. Abstract

 

  • Thomas Eade FRANZCR, Ananya Choudhury MA, PhD, MRCP, FRCR, Alan Pollack MD, PhD, Matthew Abramowitz MD, Felix M. Chinea MD, Linxin Guo BSc, MHSc, Jason Kennedy BSc, MSc, Sandra Louw, George Hruby FRANZCR, Andrew Kneebone FRANZCR, Catharine West PhD. Acute Epithelial Toxicity Is Prognostic for Improved Prostate Cancer Response to Radiation Therapy: A Retrospective, Multicenter, Cohort Study. International Journal of Radiation Oncology Biology Physics, Volume 101, Issue 4, 15 July 2018, Pages 957-963. Abstract

 

  • William A. Hall , Carmen Bergom , Reid F. Thompson , Andrew M. Baschnagel , Srinivasan Vijayakumar , Henning Willers , X. Allen Li , Christopher J. Schultz , George D. Wilson , Catharine M.L. West , Jacek Capala , C. Norman Coleman , Javier F. Torres-Roca , Joanne Weidhaas , Felix Y. Feng. Precision Oncology and Genomically Guided Radiation Therapy: A Report From the American Society for Radiation Oncology/American Association of Physicists in Medicine/National Cancer Institute Precision Medicine Conference. International Journal of Radiation Oncology Biology Physics, Volume 101, Issue 2, June 1, 2018. Abstract

 

  • Chamberlain Mbah, Kim De Ruyck, Silke De Schrijver, Charlotte De Sutter, Kimberly Schiettecatte, Chris Monten, Leen Paelinck, Wilfried De Neve, Hubert Thierens, Catharine West, Gustavo Amorim, Olivier Thas & Liv Veldeman. A new approach for modeling patient overall radiosensitivity and predicting multiple toxicity endpoints for breast cancer patients. Acta Oncologica, May 2018 https://doi.org/10.1080/0284186X.2017.1417633 . Abstract

 

  • T.Rattay, P. Symonds, S.Shokuhi. C.J. Talbot and J.B.Schnur, The Patient Perspective on Radiogenomics Testing for Breast Radiation Toxicity. Clinical Oncology, Volume 30, Issue 3, March 2018, Pages 151-157.  Abstract , Clinical Oncology

 

  • Ronan Flippot , Christophe Massard , Edouard Auclin , David Azria , Héloïse Bourien , Philippe Rochigneux , Antoine Schernberg , Loïc Verlingue , Lara Zafrani , Stéphane Vignot. Quelle vision des biomarqueurs en 2017 ? Promesses et défis de la médecine personnalisée en oncologie. Bulletin du Cancer Vol. 104/Issue 9, September 2017, Pages 735-743 Abstract

 

  • David Azria , Ariane Lapierre , Sophie Gourgou , Dirk De Ruysscher , Jacques Colinge , Philippe Lambin , Muriel Brengues , Tim Ward , Søren M. Bentzen , Hubert Thierens , Tiziana Rancati , Christopher J. Talbot , Ana Vega , Sarah L. Kerns , Christian Nicolaj Andreassen , Jenny Chang-Claude , Catharine M. L. West , Corey M. Gill , Barry S. Rosenstein. Data-Based Radiation Oncology: Design of Clinical Trials in the Toxicity Biomarkers Era. Frontiers in Oncology Vol. 7, April 27, 2017. Abstract

 

  • Ruben T H M Larue , Gilles Defraene , Dirk De Ruysscher , Philippe Lambin , Wouter van Elmpt. Quantitative radiomics studies for tissue characterization: a review of technology and methodological procedures. British Journal of Radiology Vol. 90/Issue 1070. February 2017.  Abstract

 

  • Muriel Brengues , Ariane Lapierre , Céline Bourgier , André Pèlegrin , Mahmut Özsahin , David Azria. T lymphocytes to predict radiation-induced late effects in normal tissues. Expert Review of Molecular Diagnostics Vol. 17/Issue 2, February 2017. Abstract.

 

  • Gilles Defraene , Wouter van Elmpt , Wouter Crijns , Dirk De Ruysscher. Regional variability in radiation-induced lung damage can be predicted by baseline CT numbers. Radiotherapy and Oncology Vol. 122/Issue 2, February 2017, Pages 300-306. Abstract

 

  • P Lambin, J Zindler, BGL Vanneste, L Van De Voorde, D Eekers, I Compter, K Marella Panth, Jurgen Peerlings, Ruben T.H.M. Larue, TM Deist, A Jochems, T Lustberg, J van Soest, E de Jong, AJG Even, B Reymen, N Rekers, M van Gisbergen, E Roelofs, S Carvalho, RTH Leijenaar, CML Zegers, M Jacobs, J van Timmeren, Patricia Brouwers, JA Lal, L Dubois, A Yaromina, E Jan Van Limbergen, M Berbee, W van Elmpt, C Oberije, B Ramaekers, A Dekker, LJ Boersma, F Hoebers, KM Smits, AJ Berlanga, S Walsh. Decision support systems for personalized and participative radiation oncology. Advanced Drug Delivery Reviews, Volume 109, 15 January 2017, Pages 131-153. Abstract

 

  • De Ruysscher D, Defraene G, Ramaekers BL, Lambin P, Briers E, Stobart H, Ward T, Bentzen SM, Van Staa T, Azria D, Rosenstein B, Kerns S, West C. Optimal design and patient selection for interventional trials using radiogenomic biomarkers: A REQUITE and Radiogenomics consortium statement. Radiotherapy and Oncology (the green journal). Volume 121, Issue 3, December 2016, Pages 440-446: Abstract 

 

  • Andreassen, CN; Rosenstein, BS; Kerns, SL; Ostrer, H; De Ruysscher, D; Cesaretti, JA; Barnett, GC; Dunning, AM; Dorling, L; West, CM; Burnet, NG; Elliott, R; Coles, C; Hall, E; Fachal, L; Vega, A; Gómez-Caamaño, A; Talbot, CJ; Symonds, RP; De Ruyck, K; Thierens, H; Ost, P; Chang-Claude, J; Seibold, P; Popanda, O; Overgaard, M; Dearnaley, D; Sydes, MR; Azria, D; Koch, CA; Parliament, M; Blackshaw, M; Sia, M; Fuentes-Raspall, MJ; Ramon Y Cajal, T; Barnadas, A; Vesprini, D; Gutiérrez-Enríquez, S; Mollà, M; Díe. Individual patient data meta-analysis shows a significant association between the ATM rs1801516 SNP and toxicity after radiotherapy in 5456 breast and prostate cancer patients. Radiotherapy and Oncology Vol. 121/Issue 3, December 2016, Pages 431-439. Abstract.

 

  • Carsten Herskind , Christopher J. Talbot , Sarah L. Kerns , Marlon R. Veldwijk , Barry S. Rosenstein , Catharine M.L. West. Radiogenomics: A systems biology approach to understanding genetic risk factors for radiotherapy toxicity? Cancer Letters Vol.382/Issue 1, 1 November 2016, Pages 95-109.  Review article: Article 

 

  • C. Mirjolet , J.L. Merlin , C. Dalban , P. Maingon , D. Azria. Correlation between radio-induced lymphocyte apoptosis measurements obtained from two French centres. Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique Vol. 20/Issue 5, July 2016, Pages 391-394. Abstract.

 

  • Sara Carvalho , Esther G.C. Troost , Judith Bons , Paul Menheere , Philippe Lambin , Cary Oberije. Prognostic value of blood-biomarkers related to hypoxia, inflammation, immune response and tumour load in non-small cell lung cancer – A survival model with external validation. Radiotherapy and Oncology Vol. 119/Issue 3, June 2016, pages 487-494. Abstract Paper which acknowledges REQUITE

 

  • Chamberlain Mbah, Hubert Thierens, Olivier Thas, Jan De Neve, Jenny Chang-Claude, Petra Seibold, Akke Botma, Catharine West, Kim De Ruyck. Pitfalls in prediction modelling for normal tissue toxicity in radiation therapy: an illustration with the ISE and MARIE cohorts. Manuscript accepted for publication in the International Journal of Radiation Oncology, Biology, Physics, the Red Journal. Published Online: April 01, 2016: Abstract

 

  • Qing Cheng , Erik Roelofs , Bram L.T. Ramaekers , Daniëlle Eekers , Johan van Soest , Tim Lustberg , Tim Hendriks , Frank Hoebers , Hans Paul van der Laan , Erik W. Korevaar , Andre Dekker , Johannes A. Langendijk , Philippe Lambin. Development and evaluation of an online three-level proton vs photon decision support prototype for head and neck cancer – Comparison of dose, toxicity and cost-effectiveness. Radiotherapy and Oncology Vol. 118/Issue 2, February 2016, Pages 281-285. Abstract Paper which acknowledges REQUITE

 

  • Lien Van De Voorde , Ruben Larue , Lucas Persoon , Michel Öllers , Sebastiaan Nijsten , Geert Bosmans , Maaike Berbée , Ans Swinnen , Wouter van Elmpt , Ben Vanneste , Frank Verhaegen , Philippe Lambin. The influence of gastric filling instructions on dose delivery in patients with oesophageal cancer: A prospective study. Radiotherapy and Oncology Vol. 117/Issue 3, December 2015, Pages 442-447. Abstract Paper which acknowledges REQUITE.

 

 

  • Philippe Lambin, Jaap Zindler, Ben Vanneste, Lien van de Voorde, Maria Jacobs, Daniëlle Eekers, Jurgen Peerlings, Bart Reymen, Ruben T. H. M. Larue, Timo M. Deist, Evelyn E. C. de Jong, Aniek J. G. Even, Adriana J. Berlanga, Erik Roelofs, Qing Cheng, Sara Carvalho, Ralph T. H. Leijenaar, Catharina M. L. Zegers, Evert van Limbergen, Maaike Berbee, Wouter van Elmpt, Cary Oberije, Ruud Houben, Andre Dekker, Liesbeth Boersma, Frank Verhaegen, Geert Bosmans, Frank Hoebers, Kim Smits & Sean Walsh. Modern clinical research: How rapid learning health care and cohort multiple randomised clinical trials complement traditional evidence based medicine. Acta Oncologica,Volume 54, Issue 9, October 2015, pages 1289-1300. Paper which acknowledges REQUITE

 

  • Catharina M. L. Zegers , Wouter van Elmpt , Frank J. P. Hoebers , Esther G. C. Troost , Michel C. Öllers , Felix M. Mottaghy , Philippe Lambin. Imaging of tumour hypoxia and metabolism in patients with head and neck squamous cell carcinoma. Acta OncologicaVol. 54/Issue 9, pages 1378-1384, October 2015. Paper which acknowledges REQUITE

 

 

  • T. Rancati, D. Azria, A. Brookes, T. Burr, J. Chang-Claude, S. Davidson, D. De Ruysscher, A. Dunning, R. Elliott, S. Gutiérrez Enríquez, P. Lambin, L. Lozza, B. Rosenstein, R.P. Symonds, H. Thierens, R. Valdagni, A. Vega, F. Wenz, M. Yuille, C. West. The REQUITE project: validating predictive models and biomarkers of radiotherapy toxicity to reduce side-effects. Radiotherapy and Oncology, Vol. 110, S80. Published in issue: February 2014.

 

  • T. Rancati, C. Talbot, D. Azria, A. Brookes, T. Burr, J. Chang-Claude, S. Davidson, D. De Ruysscher, A. Dunning, R.M. Elliot, S. Gutierrez-Enríquez, P. Lambin, B. Rosenstein, R.P. Symonds, H. Thierens, R. Valdagni, A. Vega, F. Wenz, M. Yuille and C. West. The REQUITE project: Validating predictive models and biomarkers of radiotherapy toxicity to reduce side effects. Journal of Clinical Oncology, 2014 Genitourinary Cancers Symposium (January 30 - February 1, 2014). Vol 32, No 4_suppl (February 1 Supplement), 2014: 276 Abstract