1. To review the trial methodology and interventions needed to design trials based on predictive models and to pick out the most suitable.
2. To perform in silico modeling of the most suitable study endpoints for each cancer type according to the findings in WP 3 and 4.
3. To write the clinical protocols.
6.1) Identify and report the most suitable trial endpoints and designs.
6.2) Report on the review of possible interventions for breast, prostate and lung cancer.
6.3) Write the draft clinical trial protocol for prostate, breast and lung cancer.